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发布时间:2023-09-14 15:56:31  本文被阅次数: 我要打印 字号:

张文利

张文利,女,硕士研究生导师,现任大连医科大学基础医学院副教授。1994年毕业于上海医科大学(现复旦大学);自 1998 年起,在我校朱正美教授和马郁芳教授的指导下开始从事自身免疫性疾病与微生物方面的研究工作;并在美国科罗拉多州立大学工作2年,及在美国加州大学洛杉矶分校接受为期3个月的英语语言培训。目前主要从事神经退行性疾病方面的研究,通讯作者和第一作者共发表SCI论文多篇,在研科研项目一项。


研究方向:

神经退行性疾病


主要承担项目:

辽宁省应用基础研究项目,2022JH2/101300084,与蛋白质分解代谢相关的小分子代谢物在帕金森病预防、诊断和干预中的作用研究,辽宁省科技厅(30万),2022-08-01至 2024-07-31。


主要代表论文(近5年):

1.Chen Y, Wu L, Liu J, Ma L, Zhang W. Adenine nucleotide translocase: Current knowledge in post-translational modifications, regulations and pathological implications for human diseases. FASEB J. 2023 Jun; 37(6): e22953. doi: 10.1096/fj.202201855RR. PMID: 37224026. (通讯作者)

2.Chen Y, Ding W, Xu Y, Li S, Zhang W. Exploratory application of an integrated topic-based curriculum in biochemistry experimental teaching. Biochem Mol Biol Educ. 2022 Nov;50(6):561-570. doi: 10.1002/bmb.21564. Epub 2022 Sep 9. PMID: 36082801.(通讯作者,IF=1.369)

3.Zhang W, Liu J, Chen Q, Ding W, Li S, Ma L. Identification of ADP/ATP Translocase 1 as a Novel Glycoprotein and Its Association with Parkinson's Disease. Neurochem Res. 2022 Nov; 47(11): 3355-3368. doi: 10.1007/s11064-022-03688-9. Epub 2022 Aug 13. PMID: 35962937. (第一作者,IF=4.414)

4.Ding W, Qi M, Ma L, Xu X, Chen Y, Zhang W. ADP/ATP translocase 1 protects against an α-synuclein-associated neuronal cell damage in Parkinson's disease model. Cell Biosci. 2021 Jul 10;11(1):130. doi: 10.1186/s13578-021-00645-x. PMID: 34246309; PMCID: PMC8272299. (通讯作者,IF=9.584)

5.Guoying Deng, Wenli Zhang, Na Ji, Yunpeng Zhai, Xiaoxia Shi, Xin Liu and Shufeng Yang. Identification of Secreted O-Mannosylated Proteins From BCG and Characterization of Immunodominant Antigens BCG_0470 and BCG_0980, Front Microbiol. 2020 Mar 13;11:407. doi: 10.3389/fmicb.2020.00407. PMID: 32231652; PMCID: PMC7082424.(并列第一作者,IF=5.640)

6.Ma L, Song J, Sun X, Ding W, Fan K, Qi M, Xu Y, Zhang W. Role of microtubule-associated protein 6 glycosylated with Gal-(β-1,3)-GalNAc in Parkinson's disease. Aging (Albany NY). 2019 Jul 9;11(13):4597-4610. doi: 10.18632/aging.102072. PMID: 31289257; PMCID: PMC6660046.(通讯作者,IF=4.831)

7.Chen Y, Xu Y, Yang S, Li S, Ding W, Zhang W. Deficiency of D-alanyl-D-alanine ligase A attenuated cell division and greatly altered the proteome of Mycobacterium smegmatis. Microbiologyopen. 2019 Mar 3:e819. (通讯作者,IF=3.142)

8.Zhang W, Li S, Ma L, Ding W, Xu Y. Identification of a novel carboxypeptidase encoded by Rv3627c that plays a potential role in mycobacteria morphology and cell division. Enzyme Microb Technol. 2019 Jul;126:32-40. (第一作者,IF=3.448)

9.Ding W, Zhang H, Xu Y, Ma L, Zhang W. Proteomic and Morphologic Evidence for Taurine-5-Bromosalicylaldehyde Schiff Base as an Efficient Anti-Mycobacterial Drug. J Microbiol Biotechnol. 2019 Aug 28;29(8):1221-1229. doi: 10.4014/jmb.1901.01021. PMID: 31370112.. 通讯作者(if=1.992)

10.Yang S, Xu Y, Wang Y, Ren F, Li S, Ding W, Ma Y, Zhang W. The Biological Properties and Potential Interacting Proteins of d-Alanyl-d-alanine Ligase A from Mycobacterium tuberculosis. Molecules. 2018 Feb 3;23(2). (通讯作者,IF=3.060)


联系方式:

2252003813@qq.com;13591799210


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